Increased Gene Copy Number of DEFA1A3 Is Associated With the Severity of Ulcerative Colitis

DEFA1A3 encodes human neutrophil peptides (HNPs) 1–3 and has multiple copy number variations (CNVs). HNPs are associated with innate immunity. Ulcerative colitis (UC), a chronic inflammatory gastrointestinal disorder, is a life-threatening condition, and predictive markers of UC severity are needed....

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Detalhes bibliográficos
Publicado no:Clin Transl Gastroenterol
Main Authors: Kanmura, Shuji, Morinaga, Yuko, Tanaka, Akihito, Komaki, Yuga, Iwaya, Hiromichi, Kumagai, Kotaro, Mawatari, Seiichi, Sasaki, Fumisato, Tanoue, Shiroh, Hashimoto, Shinichi, Sameshima, Yoichi, Ono, Yohei, Ohi, Hidehisa, Ido, Akio
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8032364/
https://ncbi.nlm.nih.gov/pubmed/33825720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14309/ctg.0000000000000331
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