A human coronavirus evolves antigenically to escape antibody immunity

There is intense interest in antibody immunity to coronaviruses. However, it is unknown if coronaviruses evolve to escape such immunity, and if so, how rapidly. Here we address this question by characterizing the historical evolution of human coronavirus 229E. We identify human sera from the 1980s a...

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Publicat a:PLoS Pathog
Autors principals: Eguia, Rachel T., Crawford, Katharine H. D., Stevens-Ayers, Terry, Kelnhofer-Millevolte, Laurel, Greninger, Alexander L., Englund, Janet A., Boeckh, Michael J., Bloom, Jesse D.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8031418/
https://ncbi.nlm.nih.gov/pubmed/33831132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009453
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