A human coronavirus evolves antigenically to escape antibody immunity

There is intense interest in antibody immunity to coronaviruses. However, it is unknown if coronaviruses evolve to escape such immunity, and if so, how rapidly. Here we address this question by characterizing the historical evolution of human coronavirus 229E. We identify human sera from the 1980s a...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Eguia, Rachel T., Crawford, Katharine H. D., Stevens-Ayers, Terry, Kelnhofer-Millevolte, Laurel, Greninger, Alexander L., Englund, Janet A., Boeckh, Michael J., Bloom, Jesse D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8031418/
https://ncbi.nlm.nih.gov/pubmed/33831132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009453
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