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IDH1 Mutations in Oligodendroglial Tumors: Comparative Analysis of Direct Sequencing, Pyrosequencing, Immunohistochemistry, Nested PCR and PNA‐Mediated Clamping PCR
Mutations in isocitrate dehydrogenase 1 (IDH1) are found in a high proportion of glial tumors and have a significant prognostic impact. Although direct sequencing has been considered to be the gold‐standard method to detect this mutation, the sensitivity of this technique has been questioned especia...
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| Pubblicato in: | Brain Pathol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8029453/ https://ncbi.nlm.nih.gov/pubmed/23072665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12000 |
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