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IDH1 Mutations in Oligodendroglial Tumors: Comparative Analysis of Direct Sequencing, Pyrosequencing, Immunohistochemistry, Nested PCR and PNA‐Mediated Clamping PCR

Mutations in isocitrate dehydrogenase 1 (IDH1) are found in a high proportion of glial tumors and have a significant prognostic impact. Although direct sequencing has been considered to be the gold‐standard method to detect this mutation, the sensitivity of this technique has been questioned especia...

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Dades bibliogràfiques
Publicat a:Brain Pathol
Autors principals: Lee, Dakeun, Suh, Yeon‐Lim, Kang, So Young, Park, Tae‐In, Jeong, Ji Yun, Kim, Se‐Hoon
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029453/
https://ncbi.nlm.nih.gov/pubmed/23072665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12000
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