Detection of EGFR mutations in circulating free DNA by PNA-mediated PCR clamping

BACKGROUND: Epidermal growth factor receptor (EGFR)-activating mutations are major determinants in predicting the tumor response to EGFR tyrosine kinase inhibitors in non-small cell lung cancer (NSCLC). Noninvasive test for the detection of EGFR mutations is required, especially in NSCLC patients fr...

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Bibliographische Detailangaben
Hauptverfasser: Kim, Hye-Ryoun, Lee, Sung Yong, Hyun, Dae-Sung, Lee, Min Ki, Lee, Hyun-Kyung, Choi, Chang-Min, Yang, Sei-Hoon, Kim, Young-Chul, Lee, Yong Chul, Kim, Sun Young, Jang, Seung Hun, Lee, Jae Cheol, Lee, Kye Young
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751150/
https://ncbi.nlm.nih.gov/pubmed/23927790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-32-50
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