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Suppressed Expression of Autophagosomal Protein LC3 in Cortical Tubers of Tuberous Sclerosis Complex

Tuberous sclerosis complex (TSC) is characterized by benign tumors and hamartomas, including cortical tubers. Hamartin and tuberin, encoded by the TSC 1 and 2 genes, respectively, constitute a functional complex that negatively regulates the mammalian target of rapamycin (mTOR) signaling pathway, ev...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Principais autores: Miyahara, Hiroaki, Natsumeda, Manabu, Shiga, Atsushi, Aoki, Hiroshi, Toyoshima, Yasuko, Zheng, Yingjun, Takeuchi, Ryoko, Murakami, Hiroatsu, Masuda, Hiroshi, Kameyama, Shigeki, Izumi, Tatsuro, Fujii, Yukihiko, Takahashi, Hitoshi, Kakita, Akiyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029364/
https://ncbi.nlm.nih.gov/pubmed/22974335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2012.00634.x
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