PATH-46. NEURONAL DIFFERENTIATION IS INDUCED BY Gli3 IN WNT- AND SHH- ACTIVATED MEDULLOBLASTOMA

BACKGROUND: We have previously investigated the expression of Gli3, a downstream target of the Sonic Hedgehog pathway, which main function is to suppress Gli1/2 in medulloblastomas. We found that Gli3 is associated with neuronal and glial differentiation in desmoplastic / nodular (D/N) type medullob...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: Natsumeda, Manabu, Miyahara, Hiroaki, Yoshimura, Junichi, Nakata, Satoshi, Tsukamoto, Yoshihiro, Watanabe, Jun, Wataya, Takafumi, Eberhart, Charles, Kakita, Akiyoshi, Fujii, Yukihiko
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2018
Sujets:
Abstracts
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216915/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.701
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires