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Alexander disease: an astrocytopathy that produces a leukodystrophy
Alexander Disease (AxD) is a degenerative disorder caused by mutations in the GFAP gene, which encodes the major intermediate filament of astrocytes. As other cells in the CNS do not express GFAP, AxD is a primary astrocyte disease. Astrocytes acquire a large number of pathological features, includi...
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| Publié dans: | Brain Pathol |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley and Sons Inc.
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8028392/ https://ncbi.nlm.nih.gov/pubmed/29740945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12601 |
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