IL-24 deficiency protects mice against bleomycin-induced pulmonary fibrosis by repressing IL-4-induced M2 program in macrophages

Idiopathic pulmonary fibrosis (IPF) is the most common type of idiopathic interstitial pneumonia and has one of the poorest prognosis. However, the molecular mechanisms underlying IPF progression remain largely unknown. In this study, we determined that IL-24, an IL-20 subfamily cytokine member, was...

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Izdano u:Cell Death Differ
Glavni autori: Rao, Li-Zong, Wang, Yi, Zhang, Lei, Wu, Guorao, Zhang, Lu, Wang, Fa-Xi, Chen, Long-Min, Sun, Fei, Jia, Song, Zhang, Shu, Yu, Qilin, Wei, Jiang-Hong, Lei, Hui-Ren, Yuan, Ting, Li, Jinxiu, Huang, Xingxu, Cheng, Bin, Zhao, Jianping, Xu, Yongjian, Mo, Bi-Wen, Wang, Cong-Yi, Zhang, Huilan
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8027679/
https://ncbi.nlm.nih.gov/pubmed/33144678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-00650-6
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