Curdione ameliorates bleomycin-induced pulmonary fibrosis by repressing TGF-β-induced fibroblast to myofibroblast differentiation

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a progressive and irreversible disease characterized by excessive fibroblast to myofibroblast differentiation with limited therapeutic options. Curdione, a sesquiterpene compound extracted from the essential oil of Curcuma aromatica Salisb, has anti...

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Vydáno v:Respir Res
Hlavní autoři: Liu, Peng, Miao, Kang, Zhang, Lei, Mou, Yong, Xu, Yongjian, Xiong, Weining, Yu, Jun, Wang, Yi
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7031930/
https://ncbi.nlm.nih.gov/pubmed/32075634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-020-1300-y
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