IL-24 deficiency protects mice against bleomycin-induced pulmonary fibrosis by repressing IL-4-induced M2 program in macrophages

Idiopathic pulmonary fibrosis (IPF) is the most common type of idiopathic interstitial pneumonia and has one of the poorest prognosis. However, the molecular mechanisms underlying IPF progression remain largely unknown. In this study, we determined that IL-24, an IL-20 subfamily cytokine member, was...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Rao, Li-Zong, Wang, Yi, Zhang, Lei, Wu, Guorao, Zhang, Lu, Wang, Fa-Xi, Chen, Long-Min, Sun, Fei, Jia, Song, Zhang, Shu, Yu, Qilin, Wei, Jiang-Hong, Lei, Hui-Ren, Yuan, Ting, Li, Jinxiu, Huang, Xingxu, Cheng, Bin, Zhao, Jianping, Xu, Yongjian, Mo, Bi-Wen, Wang, Cong-Yi, Zhang, Huilan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8027679/
https://ncbi.nlm.nih.gov/pubmed/33144678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-00650-6
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