Phage gene expression and host responses lead to infection-dependent costs of CRISPR immunity

CRISPR-Cas immune systems are widespread in bacteria and archaea, but not ubiquitous. Previous work has demonstrated that CRISPR immunity is associated with an infection-induced fitness cost, which may help explain the patchy distribution observed. However, the mechanistic basis of this cost has rem...

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Bibliografiska uppgifter
I publikationen:ISME J
Huvudupphovsmän: Meaden, Sean, Capria, Loris, Alseth, Ellinor, Gandon, Sylvain, Biswas, Ambarish, Lenzi, Luca, van Houte, Stineke, Westra, Edze R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2020
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8027618/
https://ncbi.nlm.nih.gov/pubmed/33011743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41396-020-00794-w
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