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Cryo-EM structure of the human histamine H(1) receptor/G(q) complex

Histamine receptors play important roles in various pathophysiological conditions and are effective targets for anti-allergy treatment, however the mechanism of receptor activation remain elusive. Here, we present the cryo-electron microscopy (cryo-EM) structure of the human H(1)R in complex with a...

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Dettagli Bibliografici
Pubblicato in:Nat Commun
Autori principali: Xia, Ruixue, Wang, Na, Xu, Zhenmei, Lu, Yang, Song, Jing, Zhang, Anqi, Guo, Changyou, He, Yuanzheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8027608/
https://ncbi.nlm.nih.gov/pubmed/33828102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22427-2
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