Cancer Associated Fibroblasts Promote Renal Cancer Progression Through a TDO/Kyn/AhR Dependent Signaling Pathway

Cancer associated fibroblasts (CAFs) play crucial roles in cancer development, however, the specific mechanisms of CAFs associated renal cancer progression remain poorly understood. Our study observed enriched CAFs in high degree malignant tumor tissues from renal cancer patients. These CAFs isolate...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Chen, Li-bo, Zhu, Shun-ping, Liu, Tian-pei, Zhao, Heng, Chen, Ping-feng, Duan, You-jun, Hu, Rong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8027476/
https://ncbi.nlm.nih.gov/pubmed/33842334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.628821
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