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TDO2 Promotes the EMT of Hepatocellular Carcinoma Through Kyn-AhR Pathway
Tryptophan 2,3-dioxygenase (TDO2), an enzyme involved in tryptophan (Trp) metabolism has been linked with some malignant traits of various cancers. Kyn, the main product of Trp metabolism pathway catalyzed by TDO2 and indoleamine 2,3-dioxygenase (IDO) in tumor cells, was also demonstrated to activat...
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| Publicado no: | Front Oncol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7851084/ https://ncbi.nlm.nih.gov/pubmed/33542896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.562823 |
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