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TDO2 Promotes the EMT of Hepatocellular Carcinoma Through Kyn-AhR Pathway
Tryptophan 2,3-dioxygenase (TDO2), an enzyme involved in tryptophan (Trp) metabolism has been linked with some malignant traits of various cancers. Kyn, the main product of Trp metabolism pathway catalyzed by TDO2 and indoleamine 2,3-dioxygenase (IDO) in tumor cells, was also demonstrated to activat...
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| Gepubliceerd in: | Front Oncol |
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| Hoofdauteurs: | , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Frontiers Media S.A.
2021
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7851084/ https://ncbi.nlm.nih.gov/pubmed/33542896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.562823 |
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