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Serum Zonulin Measured by Commercial Kit Fails to Correlate With Physiologic Measures of Altered Gut Permeability in First Degree Relatives of Crohn's Disease Patients

Intestinal epithelial cell tight junctions (TJs) contribute to the integrity of the intestinal barrier allowing for control of the physical barrier between external antigens or bacterial products and the internal environment. Zonula occludens-1 (ZO-1) is a protein that modulates intestinal TJs, and...

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Bibliografische gegevens
Gepubliceerd in:Front Physiol
Hoofdauteurs: Power, Namita, Turpin, Williams, Espin-Garcia, Osvaldo, Smith, Michelle I., Croitoru, Kenneth
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8027468/
https://ncbi.nlm.nih.gov/pubmed/33841181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2021.645303
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