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Serum Zonulin Measured by Commercial Kit Fails to Correlate With Physiologic Measures of Altered Gut Permeability in First Degree Relatives of Crohn's Disease Patients

Intestinal epithelial cell tight junctions (TJs) contribute to the integrity of the intestinal barrier allowing for control of the physical barrier between external antigens or bacterial products and the internal environment. Zonula occludens-1 (ZO-1) is a protein that modulates intestinal TJs, and...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Power, Namita, Turpin, Williams, Espin-Garcia, Osvaldo, Smith, Michelle I., Croitoru, Kenneth
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8027468/
https://ncbi.nlm.nih.gov/pubmed/33841181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2021.645303
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