Serum Zonulin Measured by Commercial Kit Fails to Correlate With Physiologic Measures of Altered Gut Permeability in First Degree Relatives of Crohn's Disease Patients

Intestinal epithelial cell tight junctions (TJs) contribute to the integrity of the intestinal barrier allowing for control of the physical barrier between external antigens or bacterial products and the internal environment. Zonula occludens-1 (ZO-1) is a protein that modulates intestinal TJs, and...

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Bibliographic Details
Published in:Front Physiol
Main Authors: Power, Namita, Turpin, Williams, Espin-Garcia, Osvaldo, Smith, Michelle I., Croitoru, Kenneth
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Physiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8027468/
https://ncbi.nlm.nih.gov/pubmed/33841181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2021.645303
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