Agonal Factors Distort Gene-Expression Patterns in Human Postmortem Brains

Agonal factors, the conditions that occur just prior to death, can impact the molecular quality of postmortem brains, influencing gene expression results. Our study used gene expression data of 262 samples from ROSMAP with the detailed terminal state recorded for each donor, such as fever, infection...

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Bibliografiska uppgifter
I publikationen:Front Neurosci
Huvudupphovsmän: Dai, Jiacheng, Chen, Yu, Dai, Rujia, Jiang, Yi, Tian, Jianghua, Liu, Sihan, Xu, Meng, Li, Miao, Zhou, Jiaqi, Liu, Chunyu, Chen, Chao
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2021
Ämnen:
Neuroscience
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8027124/
https://ncbi.nlm.nih.gov/pubmed/33841074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2021.614142
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