Agonal Factors Distort Gene-Expression Patterns in Human Postmortem Brains

Agonal factors, the conditions that occur just prior to death, can impact the molecular quality of postmortem brains, influencing gene expression results. Our study used gene expression data of 262 samples from ROSMAP with the detailed terminal state recorded for each donor, such as fever, infection...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Dai, Jiacheng, Chen, Yu, Dai, Rujia, Jiang, Yi, Tian, Jianghua, Liu, Sihan, Xu, Meng, Li, Miao, Zhou, Jiaqi, Liu, Chunyu, Chen, Chao
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8027124/
https://ncbi.nlm.nih.gov/pubmed/33841074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2021.614142
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