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Rhodium-Catalyzed C–H Alkenylation/Electrocyclization Cascade Provides Dihydropyridines that Serve as Versatile Intermediates to Diverse Nitrogen Heterocycles

Nitrogen heterocycles are present in approximately 60% of drugs, with non-planar heterocycles incorporating stereogenic centers being of considerable interest to the fields of medicinal chemistry, chemical biology, and synthetic methods development. Over the past several years, our laboratory has de...

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Vydáno v:Acc Chem Res
Hlavní autoři: Dongbang, Sun, Confair, Danielle N., Ellman, Jonathan A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026680/
https://ncbi.nlm.nih.gov/pubmed/33740369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.accounts.1c00027
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