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Non-canonical roles of caspase-4 and caspase-5 in heme driven- IL-1β release and cell death

Excessive release of heme from red blood cells is a key pathophysiological feature of several disease states including bacterial sepsis, malaria, and sickle cell disease. This hemolysis results in an increased level of free heme that has been implicated in the inflammatory activation of monocytes, m...

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Dades bibliogràfiques
Publicat a:J Immunol
Autors principals: Bolívar, Beatriz E., Brown-Suedel, Alexandra N., Rohrman, Brittany A., Charendoff, Chloé I., Yazdani, Vanda, Belcher, John D., Vercellotti, Gregory M., Flanagan, Jonathan M., Bouchier-Hayes, Lisa
Format: Artigo
Idioma:Inglês
Publicat: 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026643/
https://ncbi.nlm.nih.gov/pubmed/33741688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000226
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