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Non-canonical roles of caspase-4 and caspase-5 in heme driven- IL-1β release and cell death
Excessive release of heme from red blood cells is a key pathophysiological feature of several disease states including bacterial sepsis, malaria, and sickle cell disease. This hemolysis results in an increased level of free heme that has been implicated in the inflammatory activation of monocytes, m...
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| Publicado no: | J Immunol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8026643/ https://ncbi.nlm.nih.gov/pubmed/33741688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000226 |
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