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Autophagy-dependent increased ADAM10 mature protein induced by TFEB overexpression is mediated through PPARα
Nonamyloidogenic processing of amyloid precursor protein (APP) by augmenting ADAM10 is a promising therapeutic strategy for Alzheimer’s disease (AD). Therefore identification of molecular pathways that regulate ADAM10 expression is crucial. Autophagy is strongly dysregulated in AD, and TFEB was rece...
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| Publicado no: | Mol Neurobiol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8026501/ https://ncbi.nlm.nih.gov/pubmed/33417226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-020-02230-8 |
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