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Emphysema Mediated by Lung Overexpression of ADAM10

Cigarette smoking is the major risk factor for emphysema, a disorder of the lung parenchyma characterized by destruction of the alveolar walls. Current concepts of the pathogenesis of emphysema hold that the destruction of the lung parenchyma results, in part, from a local imbalance of proteases and...

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Detalhes bibliográficos
Main Authors: Saitoh, Hiroki, Leopold, Philip L., Harvey, Ben‐Gary, O'Connor, Timothy P., Worgall, Stefan, Hackett, Neil R., Crystal, Ronald G.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Inc 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4152377/
https://ncbi.nlm.nih.gov/pubmed/20443867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1752-8062.2008.00085.x
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