Aging imparts cell-autonomous dysfunction to regulatory T cells during recovery from influenza pneumonia

Regulatory T (Treg) cells orchestrate resolution and repair of acute lung inflammation and injury after viral pneumonia. Compared with younger patients, older individuals experience impaired recovery and worse clinical outcomes after severe viral infections, including influenza and SARS coronavirus...

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Dettagli Bibliografici
Pubblicato in:JCI Insight
Autori principali: Morales-Nebreda, Luisa, Helmin, Kathryn A., Torres Acosta, Manuel A., Markov, Nikolay S., Hu, Jennifer Yuan-Shih, Joudi, Anthony M., Piseaux-Aillon, Raul, Abdala-Valencia, Hiam, Politanska, Yuliya, Singer, Benjamin D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2021
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026188/
https://ncbi.nlm.nih.gov/pubmed/33600379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.141690
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