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Aging imparts cell-autonomous dysfunction to regulatory T cells during recovery from influenza pneumonia

Regulatory T (Treg) cells orchestrate resolution and repair of acute lung inflammation and injury after viral pneumonia. Compared with younger patients, older individuals experience impaired recovery and worse clinical outcomes after severe viral infections, including influenza and SARS coronavirus...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Morales-Nebreda, Luisa, Helmin, Kathryn A., Torres Acosta, Manuel A., Markov, Nikolay S., Hu, Jennifer Yuan-Shih, Joudi, Anthony M., Piseaux-Aillon, Raul, Abdala-Valencia, Hiam, Politanska, Yuliya, Singer, Benjamin D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026188/
https://ncbi.nlm.nih.gov/pubmed/33600379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.141690
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