Crosstalk between nonclassical monocytes and alveolar macrophages mediates transplant ischemia-reperfusion injury through classical monocyte recruitment

Primary graft dysfunction (PGD) is the predominant cause of early graft loss following lung transplantation. We recently demonstrated that donor pulmonary intravascular nonclassical monocytes (NCM) initiate neutrophil recruitment. Simultaneously, host-origin classical monocytes (CM) permeabilize the...

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Publicado en:JCI Insight
Main Authors: Kurihara, Chitaru, Lecuona, Emilia, Wu, Qiang, Yang, Wenbin, Núñez-Santana, Félix L., Akbarpour, Mahzad, Liu, Xianpeng, Ren, Ziyou, Li, Wenjun, Querrey, Melissa, Ravi, Sowmya, Anderson, Megan L., Cerier, Emily, Sun, Haiying, Kelly, Megan E., Abdala-Valencia, Hiam, Shilatifard, Ali, Mohanakumar, Thalachallour, Budinger, G.R. Scott, Kreisel, Daniel, Bharat, Ankit
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2021
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026186/
https://ncbi.nlm.nih.gov/pubmed/33621212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.147282
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