15-PGDH inhibition activates the splenic niche to promote hematopoietic regeneration

The splenic microenvironment regulates hematopoietic stem and progenitor cell (HSPC) function, particularly during demand-adapted hematopoiesis; however, practical strategies to enhance splenic support of transplanted HSPCs have proved elusive. We have previously demonstrated that inhibiting 15-hydr...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:JCI Insight
Huvudupphovsmän: Smith, Julianne N.P., Dawson, Dawn M., Christo, Kelsey F., Jogasuria, Alvin P., Cameron, Mark J., Antczak, Monika I., Ready, Joseph M., Gerson, Stanton L., Markowitz, Sanford D., Desai, Amar B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2021
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026178/
https://ncbi.nlm.nih.gov/pubmed/33600377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.143658
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk