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NanoSINC-seq dissects the isoform diversity in subcellular compartments of single cells

Alternative mRNA isoforms play a key role in generating diverse protein isoforms. To dissect isoform usage in the subcellular compartments of single cells, we introduced an novel approach, nanopore sequencing coupled with single-cell integrated nuclear and cytoplasmic RNA sequencing, that couples mi...

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Bibliografische gegevens
Gepubliceerd in:Sci Adv
Hoofdauteurs: Oguchi, Yusuke, Ozaki, Yuka, Abdelmoez, Mahmoud N., Shintaku, Hirofumi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Association for the Advancement of Science 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026137/
https://ncbi.nlm.nih.gov/pubmed/33827812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abe0317
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