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Functional regulation of the structure-specific endonuclease FEN1 by the human cytomegalovirus protein IE1 suggests a role for the re-initiation of stalled viral replication forks

Flap endonuclease 1 (FEN1) is a member of the family of structure-specific endonucleases implicated in regulation of DNA damage response and DNA replication. So far, knowledge on the role of FEN1 during viral infections is limited. Previous publications indicated that poxviruses encode a conserved p...

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Publicado en:PLoS Pathog
Main Authors: Schilling, Eva-Maria, Scherer, Myriam, Rothemund, Franziska, Stamminger, Thomas
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8026080/
https://ncbi.nlm.nih.gov/pubmed/33770148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009460
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