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Cryo-EM of kinesin-binding protein: challenges and opportunities from protein-surface interactions

Kinesin-binding protein (KBP) is an important selective inhibitor of specific kinesin family members and its genetic disruption causes Goldberg–Shprintzen syndrome. Cryo-electron microscopy (cryo-EM) has recently been used to reveal the structure of KBP alone (72 kDa) and in complex with the motor d...

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Vydáno v:Acta Crystallogr D Struct Biol
Hlavní autoři: Atherton, Joseph, Moores, Carolyn A.
Médium: Artigo
Jazyk:Inglês
Vydáno: International Union of Crystallography 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8025885/
https://ncbi.nlm.nih.gov/pubmed/33825702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798321001935
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