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Cryo-EM structure of the Ustilago maydis kinesin-5 motor domain bound to microtubules

In many eukaryotes, kinesin-5 motors are essential for mitosis, and small molecules that inhibit human kinesin-5 disrupt cell division. To investigate whether fungal kinesin-5s could be targets for novel fungicides, we studied kinesin-5 from the pathogenic fungus Ustilago maydis. We used cryo-electr...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Struct Biol
Päätekijät: von Loeffelholz, Ottilie, Moores, Carolyn Ann
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Academic Press 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6722389/
https://ncbi.nlm.nih.gov/pubmed/31288039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2019.07.003
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