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Cryo-EM structure of the Ustilago maydis kinesin-5 motor domain bound to microtubules
In many eukaryotes, kinesin-5 motors are essential for mitosis, and small molecules that inhibit human kinesin-5 disrupt cell division. To investigate whether fungal kinesin-5s could be targets for novel fungicides, we studied kinesin-5 from the pathogenic fungus Ustilago maydis. We used cryo-electr...
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| Vydáno v: | J Struct Biol |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Academic Press
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6722389/ https://ncbi.nlm.nih.gov/pubmed/31288039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2019.07.003 |
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