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Total Synthesis of (–)-Maximiscin

A short, enantioselective synthesis of (–)-maximiscin, a structurally-intriguing metabolite of mixed biosynthetic origin, is reported. A retrosynthetic analysis predicated on maximizing ideality and efficiency led to several unusual disconnections and tactics. Formation of the central highly-oxidize...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: McClymont, Kyle S., Wang, Feng-Yuan, Minakar, Amin, Baran, Phil S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8025790/
https://ncbi.nlm.nih.gov/pubmed/32338003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c03202
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