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Total synthesis of taxane terpenes: cyclase phase

A full account of synthetic efforts toward a lowly oxidized taxane framework is presented. A non-natural taxane, dubbed “taxadienone”, was synthesized as our first entry into the taxane family of diterpenes. The final synthetic sequence illustrates a seven-step, gram-scale and enantioselective route...

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Detalhes bibliográficos
Main Authors: Ishihara, Yoshihiro, Mendoza, Abraham, Baran, Phil S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685884/
https://ncbi.nlm.nih.gov/pubmed/23794756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2013.04.028
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