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Enantioselective C2-Allylation of Benzimidazoles Using 1,3-Diene Pronucleophiles

Although substituted benzimidazoles are common substructures in bioactive small molecules, synthetic methods for their derivatization are still limited. Previously, several enantioselective allylation reactions of benzimidazoles have been reported that functionalize the nucleophilic nitrogen atom. H...

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Detalhes bibliográficos
Publicado no:Org Lett
Main Authors: Knippel, James Levi, Ye, Yuxuan, Buchwald, Stephen L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8025295/
https://ncbi.nlm.nih.gov/pubmed/33646778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.1c00306
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