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Enantioselective C2-Allylation of Benzimidazoles Using 1,3-Diene Pronucleophiles

Although substituted benzimidazoles are common substructures in bioactive small molecules, synthetic methods for their derivatization are still limited. Previously, several enantioselective allylation reactions of benzimidazoles have been reported that functionalize the nucleophilic nitrogen atom. H...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Org Lett
Main Authors: Knippel, James Levi, Ye, Yuxuan, Buchwald, Stephen L.
Format: Artigo
Jezik:Inglês
Izdano: 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8025295/
https://ncbi.nlm.nih.gov/pubmed/33646778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.1c00306
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