Intraepithelial Lymphocytes Suppress Intestinal Tumor Growth by Cell-to-Cell Contact via CD103/E-Cadherin Signal

BACKGROUND & AIMS: The reason why small intestinal cancer is rarer than colorectal cancer is not clear. We hypothesized that intraepithelial lymphocytes (IELs), which are enriched in the small intestine, are the closest immune cells to epithelial cells, exclude tumor cells via cell-to-cell conta...

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Publicado en:Cell Mol Gastroenterol Hepatol
Main Authors: Morikawa, Ryo, Nemoto, Yasuhiro, Yonemoto, Yuki, Tanaka, Shohei, Takei, Yuria, Oshima, Shigeru, Nagaishi, Takashi, Tsuchiya, Kiichiro, Nozaki, Kengo, Mizutani, Tomohiro, Nakamura, Tetsuya, Watanabe, Mamoru, Okamoto, Ryuichi
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2021
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8025200/
https://ncbi.nlm.nih.gov/pubmed/33515805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2021.01.014
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