TNFAIP3 promotes survival of CD4 T cells by restricting MTOR and promoting autophagy

Autophagy plays important roles in metabolism, differentiation, and survival in T cells. TNFAIP3/A20 is a ubiquitin-editing enzyme that is thought to be a negative regulator of autophagy in cell lines. However, the role of TNFAIP3 in autophagy remains unclear. To determine whether TNFAIP3 regulates...

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Vydáno v:Autophagy
Hlavní autoři: Matsuzawa, Yu, Oshima, Shigeru, Takahara, Masahiro, Maeyashiki, Chiaki, Nemoto, Yasuhiro, Kobayashi, Masanori, Nibe, Yoichi, Nozaki, Kengo, Nagaishi, Takashi, Okamoto, Ryuichi, Tsuchiya, Kiichiro, Nakamura, Tetsuya, Ma, Averil, Watanabe, Mamoru
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2015
Témata:
Basic Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4590588/
https://ncbi.nlm.nih.gov/pubmed/26043155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1055439
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