Insert L1 is a central hub for allosteric regulation of USP1 activity

During DNA replication, the deubiquitinating enzyme USP1 limits the recruitment of translesion polymerases by removing ubiquitin marks from PCNA to allow specific regulation of the translesion synthesis (TLS) pathway. USP1 activity depends on an allosteric activator, UAF1, and this is tightly contro...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:EMBO Rep
Main Authors: Dharadhar, Shreya, van Dijk, Willem J, Scheffers, Serge, Fish, Alexander, Sixma, Titia K
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2021
Fag:
Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024992/
https://ncbi.nlm.nih.gov/pubmed/33619839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202051749
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker