Načítá se...

Insert L1 is a central hub for allosteric regulation of USP1 activity

During DNA replication, the deubiquitinating enzyme USP1 limits the recruitment of translesion polymerases by removing ubiquitin marks from PCNA to allow specific regulation of the translesion synthesis (TLS) pathway. USP1 activity depends on an allosteric activator, UAF1, and this is tightly contro...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:EMBO Rep
Hlavní autoři: Dharadhar, Shreya, van Dijk, Willem J, Scheffers, Serge, Fish, Alexander, Sixma, Titia K
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024992/
https://ncbi.nlm.nih.gov/pubmed/33619839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202051749
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!