HSP90 identified by a proteomic approach as druggable target to reverse platinum resistance in ovarian cancer

Acquired resistance to platinum (Pt)‐based therapies is an urgent unmet need in the management of epithelial ovarian cancer (EOC) patients. Here, we characterized by an unbiased proteomics method three isogenic EOC models of acquired Pt resistance (TOV‐112D, OVSAHO, and MDAH‐2774). Using this approa...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Lombardi, Rita, Sonego, Maura, Pucci, Biagio, Addi, Laura, Iannelli, Federica, Capone, Francesca, Alfano, Luigi, Roca, Maria Serena, Milone, Maria Rita, Moccia, Tania, Costa, Alice, Di Gennaro, Elena, Bruzzese, Francesca, Baldassarre, Gustavo, Budillon, Alfredo
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024727/
https://ncbi.nlm.nih.gov/pubmed/33331136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12883
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