HSP90 identified by a proteomic approach as druggable target to reverse platinum resistance in ovarian cancer

Acquired resistance to platinum (Pt)‐based therapies is an urgent unmet need in the management of epithelial ovarian cancer (EOC) patients. Here, we characterized by an unbiased proteomics method three isogenic EOC models of acquired Pt resistance (TOV‐112D, OVSAHO, and MDAH‐2774). Using this approa...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Oncol
Egile Nagusiak: Lombardi, Rita, Sonego, Maura, Pucci, Biagio, Addi, Laura, Iannelli, Federica, Capone, Francesca, Alfano, Luigi, Roca, Maria Serena, Milone, Maria Rita, Moccia, Tania, Costa, Alice, Di Gennaro, Elena, Bruzzese, Francesca, Baldassarre, Gustavo, Budillon, Alfredo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2021
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024727/
https://ncbi.nlm.nih.gov/pubmed/33331136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12883
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