CARD10 cleavage by MALT1 restricts lung carcinoma growth in vivo

CARD-CC complexes involving BCL10 and MALT1 are major cellular signaling hubs. They govern NF-κB activation through their scaffolding properties as well as MALT1 paracaspase function, which cleaves substrates involved in NF-κB regulation. In human lymphocytes, gain-of-function defects in this pathwa...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncogenesis
Prif Awduron: Israël, Laura, Glück, Anton, Berger, Marjorie, Coral, Marine, Ceci, Melanie, Unterreiner, Adeline, Rubert, Joëlle, Bardet, Maureen, Ginster, Stefanie, Golding-Ochsenbein, Alexandra M., Martin, Kea, Hoyler, Thomas, Calzascia, Thomas, Wieczorek, Grazyna, Hillenbrand, Rainer, Ferretti, Stéphane, Ferrero, Enrico, Bornancin, Frédéric
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2021
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024357/
https://ncbi.nlm.nih.gov/pubmed/33824280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-021-00321-2
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