SLAMF receptors negatively regulate B cell receptor signaling in chronic lymphocytic leukemia via recruitment of prohibitin-2

We identified a subset of Chronic Lymphocytic Leukemia (CLL) patients with high Signaling Lymphocytic Activation Molecule Family (SLAMF) receptor-related signaling that showed an indolent clinical course. Since SLAMF receptors play a role in NK cell biology, we reasoned that these receptors may impa...

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Bibliographic Details
Published in:Leukemia
Main Authors: von Wenserski, Lisa, Schultheiß, Christoph, Bolz, Sarah, Schliffke, Simon, Simnica, Donjete, Willscher, Edith, Gerull, Helwe, Wolters-Eisfeld, Gerrit, Riecken, Kristoffer, Fehse, Boris, Altfeld, Marcus, Nollau, Peter, Binder, Mascha
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024197/
https://ncbi.nlm.nih.gov/pubmed/32826957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-020-01025-z
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