Next-Generation Sequencing of T and B Cell Receptor Repertoires from COVID-19 Patients Showed Signatures Associated with Severity of Disease

We profiled adaptive immunity in COVID-19 patients with active infection or after recovery and created a repository of currently >14 million B and T cell receptor (BCR and TCR) sequences from the blood of these patients. The B cell response showed converging IGHV3-driven BCR clusters closely asso...

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Bibliografiske detaljer
Udgivet i:Immunity
Main Authors: Schultheiß, Christoph, Paschold, Lisa, Simnica, Donjete, Mohme, Malte, Willscher, Edith, von Wenserski, Lisa, Scholz, Rebekka, Wieters, Imke, Dahlke, Christine, Tolosa, Eva, Sedding, Daniel G., Ciesek, Sandra, Addo, Marylyn, Binder, Mascha
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Inc. 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7324317/
https://ncbi.nlm.nih.gov/pubmed/32668194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2020.06.024
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