RNA editing contributes to epitranscriptome diversity in chronic lymphocytic leukemia

RNA editing—primarily conversion of adenosine to inosine (A > I)—is a widespread posttranscriptional mechanism, mediated by Adenosine Deaminases acting on RNA (ADAR) enzymes to alter the RNA sequence of primary transcripts. Hence, in addition to somatic mutations and alternative RNA splicing, RNA...

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Pubblicato in:Leukemia
Autori principali: Gassner, Franz J., Zaborsky, Nadja, Buchumenski, Ilana, Levanon, Erez Y., Gatterbauer, Matthias, Schubert, Maria, Rauscher, Stefanie, Hebenstreit, Daniel, Nadeu, Ferran, Campo, Elias, Egle, Alexander, Greil, Richard, Geisberger, Roland
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024191/
https://ncbi.nlm.nih.gov/pubmed/32728184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-020-0995-6
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