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Structural basis for dimerization quality control
Most quality control pathways target misfolded proteins to prevent toxic aggregation and neurodegeneration (1). Dimerization quality control (DQC) further improves proteostasis by eliminating complexes of aberrant composition (2), yet how it detects incorrect subunits is still unknown. Here, we prov...
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| Udgivet i: | Nature |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8024055/ https://ncbi.nlm.nih.gov/pubmed/32814905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2636-7 |
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