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Unmasking coupling between channel gating and ion permeation in the muscle nicotinic receptor

Whether ion channel gating is independent of ion permeation has been an enduring, unresolved question. Here, applying single channel recording to the archetypal muscle nicotinic receptor, we unmask coupling between channel gating and ion permeation by structural perturbation of a conserved intramemb...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Strikwerda, John R, Sine, Steven M
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8024024/
https://ncbi.nlm.nih.gov/pubmed/33821794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.66225
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